In the bone marrow the most important elements of the niche appear to be osteoblasts, whilst a less defined population of fibroblasts regulates the maturation of immature T cells in the thymus. 骨髓中壁龛最重要的成分是成骨细胞,同时一类型成纤维细胞调控胸腺幼T淋巴细胞的成熟。
This recent study indicates that the first niche for expansion of blood stem cells is the placenta's vascular labyrinth, where oxygen and nutrients are exchanged between the mother and the fetus. 这项最近的研究显示,造血干细胞扩散的第一个适宜位置是胎盘的血管迷路,那里有母亲和胎儿间的氧气和养分交换。
Stem Cell Niche and Its Roles in Proliferation and Differentiation of Stem Cells 干细胞niche及其在干细胞增殖分化中的作用
The standard view is that the niche shapes stem cells, not vice versa. 以往传统的观点认为是这个生态龛位形成了干细胞,反之则不成立。
The Progress about Influence of Niche on the Differentiation of Neural Stem Cells 微环境影响神经干细胞分化的研究进展
Accompanying with further extension in the investigation of stem cells, the effects of niche that serves as their microenvironment in tissue on the functions of stem cells attract more and more attention. 随着干细胞研究的不断深入,人们愈来愈重视干细胞在机体组织中的居住环境&壁龛(niche)对干细胞的影响。
This review focuses on the stem cells niches and genes regulating the hES differentiation toward germ cells, as well as the recent advance and application on the reproductive medicine and therapy of infertility. 本文从影响人胚胎干细胞体外向生殖系分化的基因调控和干细胞小生境(niche)方面进行综述,并指出胚胎干细胞在生殖医学及不孕治疗中的研究方向和应用前景。
Host vascular niche of infarcted myocardium affects the effects of intracoronary transplantation of bone marrow stem cells on myocardial repair 梗死心肌血管微环境对经冠状动脉内移植骨髓干细胞疗效的影响
Objective Somatic stem cells ( SSCs) have the capability of self-renewal, and reside in a microenvironment named "niche" after their generation, in which the features of "stem cells" are kept. 成体干细胞是一类具有自我更新能力的细胞,他们自产生后就寄居在能够使细胞维持干细胞特性的龛状微环境(niche)中。
Niche theory tells that, more of two species '( ecological cells) niche overlap, there can be more intense competition, and the result is the survival of the fittest. 生态位理论告诉我们,两个物种(生态元)的生态位重叠越多,竞争越激烈,竞争的结果是优胜劣汰。
Study the structure and function of hepatic stem cell niche will be propitious to fully stimulate the repair potential of endogenous stem cells in liver regeneration. 深入研究肝脏干细胞niche的结构与功能将充分激发内源性肝脏干细胞在肝脏再生中的修复潜能。
In conclusion, RA can promote ES differentiation into germ cell. ( 3) ES cells developed in the specific niche. The proliferation and differentiation of ES cells are affected by the interaction between variety of matrix proteins and other cells. ES细胞在体内特定小生境中发育,其内各种基质蛋白与其他细胞相互作用影响ES细胞的增殖分化。
Human hematopoiesis is a very complex and multistep developmental process that starts from the level of pluripotent hematopoietic stem cells ( HSCs) at bone marrow microenvironment ( HSCs niche) and terminates with the production of erythrocytes. 人的造血分化是一个极复杂且多步骤的发展过程,它起始于多能造血干细胞(HSCs)在骨髓微环境(HSCsniche)中的产生,以红细胞生成为终止。
As one of the important supporting cells of liver stem cell niche, the role and mechanism of hepatic stellate cells ( HSCs) has not been elucidated in liver regeneration. 肝星状细胞(Hepaticstellatecells,HSCs)作为肝脏干细胞niche中重要的支持细胞在肝脏再生中的作用及机制尚未阐明。
Stem cell niche is specific living microenvironment for stem cells, maintain and regulate stem cell biological characteristics, and keep them in the balance of resting state, self-renewal and differentiation. 干细胞生存微环境(stemcellniche)是干细胞生活的特定环境,维持并调节干细胞的生物学特性,使之在静息态、自我更新和分化上保持平衡。